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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZFYVE26
All Species:
12.12
Human Site:
Y124
Identified Species:
38.1
UniProt:
Q68DK2
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q68DK2
NP_056161.2
2539
284636
Y124
E
N
I
L
E
E
L
Y
E
T
L
T
Q
G
A
Chimpanzee
Pan troglodytes
XP_001138003
2539
284458
Y124
E
N
I
L
E
E
L
Y
E
T
L
T
Q
G
A
Rhesus Macaque
Macaca mulatta
XP_001107907
2539
284410
Y124
E
N
I
L
E
E
L
Y
E
T
L
T
Q
G
A
Dog
Lupus familis
XP_547867
2546
284753
Y124
E
D
I
F
K
E
L
Y
E
A
L
A
Q
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q5DU37
2529
282942
P116
E
D
L
Q
G
D
I
P
E
T
I
L
K
E
L
Rat
Rattus norvegicus
NP_001101508
2542
284197
F124
E
T
I
L
K
E
L
F
E
T
L
A
Q
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421195
2572
291238
F125
E
E
V
L
K
E
L
F
E
A
Y
V
C
T
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002664236
2399
267268
E44
Q
L
G
E
A
R
A
E
D
P
H
S
P
R
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.5
86.3
N.A.
82.4
82.1
N.A.
N.A.
61.4
N.A.
45
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
98.4
92
N.A.
89.5
89
N.A.
N.A.
75.1
N.A.
60.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
53.3
N.A.
20
66.6
N.A.
N.A.
33.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
66.6
N.A.
60
80
N.A.
N.A.
53.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
0
13
0
0
25
0
25
0
0
38
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% C
% Asp:
0
25
0
0
0
13
0
0
13
0
0
0
0
13
13
% D
% Glu:
88
13
0
13
38
75
0
13
88
0
0
0
0
13
0
% E
% Phe:
0
0
0
13
0
0
0
25
0
0
0
0
0
0
0
% F
% Gly:
0
0
13
0
13
0
0
0
0
0
0
0
0
50
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% H
% Ile:
0
0
63
0
0
0
13
0
0
0
13
0
0
0
0
% I
% Lys:
0
0
0
0
38
0
0
0
0
0
0
0
13
0
0
% K
% Leu:
0
13
13
63
0
0
75
0
0
0
63
13
0
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
38
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
13
0
13
0
0
13
0
13
% P
% Gln:
13
0
0
13
0
0
0
0
0
0
0
0
63
0
13
% Q
% Arg:
0
0
0
0
0
13
0
0
0
0
0
0
0
13
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% S
% Thr:
0
13
0
0
0
0
0
0
0
63
0
38
0
13
13
% T
% Val:
0
0
13
0
0
0
0
0
0
0
0
13
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
13
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _